You may find more results for this query on our sister sites: Dx and Precision Oncology News. NEW YORK — Sex-specific gene regulatory features appear to turn up extensively in human tissues, according to a new systems biology-based analysis. From the resulting set of almost 8, networks, they documented apparent sex-related differences in transcription factor targeting and activity despite relatively subtle sex-related expression differences within most tissues considered. They further noted that these findings "underline the importance of considering systems-level differences in gene regulation to understand sex differences contributing to health and disease. The team suggested that the new collection of gene regulatory networks may help to interpret findings from future studies of biology and disease through a sex- and tissue-specific lens, moving investigators closer to the goal of designing clinical and research studies with participant sex, and its effects, in mind.

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